MLB : Seattle Mariners vs Houston Astros Odds & Prediction

Game Info: May 22, 2025 8:10PM EDT @ Daikin Park

Seattle appears to have hit a groove, possessing strong road performances, while Houston is trying to rebound after some tough defeats. Both squads are missing key players but competitive enough to keep this contest either team could win wide open.

Betting Odds and Info

These are the latest odds as of writing:

Moneyline: Mariners 1.74 , Astros 2.21

Spread: Mariners -1.5 , Astros +1.5

Over/Under: 8.5

Team Recent Performance

Seattle Mariners

They managed to top Chicago 6-5 on May 22 but were not able to cover the spread of -1.5 with the game total going above 8.5 runs. They registered a loss of 0-1 to Minnesota on May 21 with missing spread of -1.5 in a game that finished under 8.5. They bopped back on May 20 with a 5-1 score line to cover the -1.5 and lapsed under 8 runs. On May 19, they rocked the Padres’ world with a 6-1 win and then followed it up with a 4-1 shellacking of the same team on May 18, covering the +1.5 spread on both games which, by the way, end under each of the totals.

Houston Astros

The team suffered a loss to the Rays on May 22nd, 4-8 by missing the -1.5 spread while the over for the game broke at 8.5 runs. Their lost match on May 21st was 2-3 but the spread of +1.5 was made over and the total came under using 9. The last date they played was May 20; the score was already 4-3, again covering +1.5 while the total fell under 9. They won against the Rangers 4-3 with no cover for -1.5 on May 19. On May 18, they lost 1-5, also missing the -1.5 covers. All Texas games were below 8 runs.

Team Head-to-Head Matchup

The numbers are almost identical in the matchup between the Seattle Mariners and the Houston Astros. The Mariners average 3.70 runs per game while the Astros turn 3.20. The hits are also almost equal: Seattle hit 6.60, Houston 6.50. Seattle averages slightly better in walks per game than Houston (3.30 to 2.60), but has a big strikeout advantage (9.80 to 8.30). Both teams are at 3-5-2 under/over totals.

Team Injuries Update

Seattle Mariners

Victor Robles (OF, shoulder), Logan Gilbert (P, elbow), Bryce Miller (P, elbow), and George Kirby (P, shoulder) are out.

Houston Astros

Taylor Trammell (OF, calf injury), Pedro Leon (OF, knee), Cristian Javier (P, elbow), Luis Garcia (P, elbow), J.P. France (P, shoulder), and Spencer Arrighetti (P, thumb) are out.

SPORTBOOK.AG’s Prediction

The Seattle Mariners will win but the Houston Astros will cover the spread with the total staying under 8.5.

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