MLB: Houston Astros at Detroit Tigers Odds & Prediction

Game Info: Monday, August 18, 2025, 6:40 PM ET, Comerica Park, Detroit, Michigan

Get pumped for an awesome game this Monday night as the Houston Astros head to Comerica Park to take on the Detroit Tigers. The first pitch is scheduled for 6:40 PM ET, and if you’ve been keeping an eye on the AL playoff race like I have, you know this Astros vs. Tigers game could be crucial as we move forward. Houston is in pursuit of the West title, while Detroit is fighting for a Wild Card spot. The stakes are high, and so is the potential payoff.

Betting Odds

Moneyline: Astros +120 | Tigers -142

Run Line: Astros +1.5 (-162) | Tigers -1.5 (+138)

Total Runs (O/U): 8.5 (Over -108 / Under -112)

The betting lines have changed a little since Sunday night, and I wouldn’t be surprised if the wise bets start leaning towards the Over as we get closer to game time.

Astros Betting Preview

Houston has been steady, and Hunter Brown plays a big role in that. He heads into this Astros vs. Tigers matchup with a 9-5 record, a solid 2.51 ERA, and 160 strikeouts across 136.1 innings. Lately, he’s been especially strong, allowing just 3 earned runs in his last two games. Going up against a Tigers lineup that ranks in the middle offensively, Brown certainly holds the upper hand.

The Astros are still a serious offensive threat. Yordan Álvarez is back in top shape and hitting the ball with power, while José Altuve remains the core of this lineup. They work through their at-bats, capitalize on errors, and excel in clutch situations. Considering the unpredictability of Detroit’s bullpen, Houston’s experience and composure might just tip the scales.

Tigers Betting Preview

I really like this Tigers team. They’re young, eager, and they never give up. Tarik Skubal is the real deal. He has ace-level skills and the right mindset to go with it. If Detroit wants to win this matchup, it’ll be because Skubal goes deep and keeps Houston’s hitters at bay.

But here’s the thing: Detroit’s bullpen has disappointed me more than a couple of times this season. They’ve blown late leads and struggled with their control. When up against a team like Houston that shines in the late innings, that’s certainly a red flag. Still, Detroit has been doing well at home, especially as underdogs, so there’s some potential if you believe in Skubal.

Matchup/League Facts

The Astros have gone 5-5 against the Tigers in their last 10 matchups.

The Tigers are 17-8 against the spread in their previous 25 home games when they’re the underdogs.

The Over has been successful in 6 out of the Tigers’ last 10 games, and the Astros have also hit the Over 7 times in their last 10 games.

Houston is sitting at 5th in MLB for OPS, while Detroit is at 17th.

Astros at Tigers Prediction

This matchup between the Astros and Tigers looks like a trap for casual bettors. Skubal might grab some attention, but Houston’s depth and experience definitely give them the upper hand. I’m betting on the Astros at +120 on the moneyline. Plus, I believe the Over 8.5 is a solid wager. Both teams have shown they can score runs, and I’m not too sure about Detroit’s bullpen holding it together in the later innings.

Sportbook.AG Final Prediction: Astros ML (+120) Bonus Lean: Over 8.5